Association between life’s essential 8 and periodontitis: evidence from NHANES 2009–2014

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Abstract Objectives

To explore the relationship between Life’s Essential 8 (LE-8) and periodontitis, specifically focusing on identifying the specific factors within LE-8 significantly linked to periodontitis.

Materials and methods

This cross-sectional study utilized data from the National Health and Nutrition Examination Survey (2009–2014), involving 8160 participants with available LE-8 metrics and periodontal examination results. The LE-8 metrics, encompassing diet, physical activity, nicotine exposure, sleep health, body mass index, blood liquids, blood glucose, and blood pressure were collected for analysis. Periodontitis diagnosis followed CDC-AAP guidelines.

Results

4049 subjects with periodontitis (mean age, 54.80 years; 57.93% male) and 4111 subjects without periodontitis (mean age, 48.66 years; 42.61% male) were included in this study. Periodontitis subjects had lower total LE-8 scores (64.62 [63.94, 65.30]) than periodontitis-free subjects (71.34 [70.65, 72.03]). The risk of periodontitis risk significantly decreased with increasing LE-8 score. Specific factors within LE-8, including avoidance of nicotine (Adjusted

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